Research of Cell Biology and Immunology
The aim of the research performed at CBI is to integrate fundamental knowledge on the immune system of animals and humans with applications in dietary-based immunomodulation, development of immunotherapies and vaccination strategies to maintain or improve health.
By using a comparative approach between veterinary species and humans we generate tools and novel mechanistic insights that lead to a better understanding of the immune system during health and disease. This knowledge forms the basis of immune modulation strategies that can be applied to strengthen the immune system and improve the immune mediated protection of animals and humans against infections or other environmental challenges.
Strategic plan WUR
CBI performs cell biological and immunological studies that fit (at least) one of three major research lines, which align with the research theme “Healthy and safe food for healthy lives“ and investment theme “Global One Health” from the strategic plan of Wageningen University & Research.
Research themes
(Food) allergy
At CBI we investigate the immunological mechanisms of allergy, the effect of food processing on food allergy, as well as cross-reactive allergies between known allergens and (novel) food proteins
Immunomodulation by food and feed
We focus on immunomodulatory effects of food and feed-components, as well as mucosal immunology projects, focussing on immune function in the gastrointestinal and respiratory tract.
Veterinary immunology
Veterinary immunology is the cornerstone of animal health and welfare, food security, and public health. Within CBI we study the function of immune cells in livestock and companion animals.
Immune cell dynamics
CBI works with a range of imaging modalities, incl. fluorescence, MRI, PET, SPECT, ultrasound and photoacoustic imaging in different disease models, particularly cancer and cardiovascular diseases.
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