Host-Microbe Interactomics
Our research ranges from work on the molecular mechanisms of diseases caused by pathogenic bacteria to the interactions between and beneficial bacteria and their human or animal hosts. The group, with chair Jerry Wells, combines expertise in cell biology, immunology, microbiology and functional genomics to further our understanding of the molecular interactions occurring in the cross-talk between microbes and their hosts.
Research
The Host-Microbe Interactomics Group works at the heart of host-pathogen and host-microbiota research in health and disease, and performs research on vaccines and antimicrobials. Our research focusses for example on bacterial interaction iwth immune cells and improving the perfromance of lactic acid bacteria. Our research themes:
- Innate defence mechanisms in the small intestine
- Bacterial interactions with immune cells
- Discovery of novel antimicrobials
- Virulence and pathogenesis of Streptococcus suis
- Microbiota analysis
- Zebrafish: a model to study dysbiosis
- In-silico research
- Improving lactic acid bacteria performance
- Pesticides, microbes and hosts
Education
Education by Host-Microbe Interactomics
The Host-Microbe Interactomics Group provides education and training at the BSc, MSc, PhD level in basic and applied aspects of research on biology of infectious diseases, beneficial host-microbe interactions, and approaches to combating infectious diseases e.g. vaccination and antimicrobials.
Publications & Projects
The fundamental research at Wageningen University & Research is conducted by chair groups. Each chair group, under leadership of a professor, has its own area of expertise. All chair groups share a common research domain: healthy food and living environment. Wageningen University & Research is comprised of one faculty that is divided into five departments.
Projects of Host-Microbe Interactomics cover various topics in its own area of expertise. Outcomes of these studies are regularly published in scientific journals. You can find all publications and projects in Wageningen Library.
Highlighted publications
- Culturomics of the pig tonsil microbiome identifies new species and an untapped source of novel antimicrobials
- Dietary convergence induces individual responses in faecal microbiome composition
- Genome-Wide Identification of Conditionally Essential Genes Supporting Streptococcus suis Growth in Serum and Cerebrospinal Fluid
Chair Holder
Jerry Wells is professor ansd chair of Host-Microbe Interactomics. His research focusses on bacterial metabolism and the prevention of Streptococcus.
prof.dr. JM (Jerry) Wells
Professor / Chairholder
People of Host-Microbe Interactomics
Each chair group of Wageningen University & Research, under leadership of a professor, has its own area of expertise. Meet the people of Host-Microbe Interactomics.
