Nematology

The Laboratory of Nematology, led by Geert Smant, studies the biology of nematodes (roundworms), and associated organisms, to understand and predict their functioning in agricultural and natural ecosystems. We focus on nematodes as key factors in soil resilience and nutrient cycling, and as a persistent threat to animal, human and plant health.
Research themes
Soil health
We investigate the complex soil food web, which includes microbes, plant roots and nematodes, to understand how soil life supports nutrient cycling, plant growth and carbon storage.
Plant health
We study how plant-parasitic nematodes invade and manipulate their host plants, suppressing plant defences and forming specialised feeding sites. By uncovering the molecular and cellular mechanisms, we aim to improve crop resistance.
Human and animal health
We design vaccines or biopharmaceuticals against animal-parasitic nematodes. In parallel, we use nematodes to investigate human diseases like Parkinson’s.
Education innovation
Our education innovation focus on themes such as peer feedback, academic writing, self-regulation, boundary crossing and career orientation.
Education by Nematology

Education by Nematology
At Nematology, our education is focused on training future scientists to contribute to the development of sustainable food production systems and prevention of disease in humans and animals.
Publications & Projects
With our research we aim to contribute to the development of sustainable food production systems as well as to prevent disease in humans and animals. To do so, we work on projects within soil health, plant health and human and animal health. We publish our findings in scientific journals, professional journals, scientific and popular books, and proceedings.
Highlighted publications
- Soil nematode abundance and functional group composition at a global scale
- Highly efficient transgene-free ErCas12a RNP-protoplast genome editing and single-cell regeneration in Nicotiana benthamiana for glyco-engineering
- Gpa2 detects potato cyst nematode effector RBP-1 in the cytoplasm yet requires a nucleocytoplasmic balance for cell death
Chair Holder
Geert Smant has been Chair of Nematology since 2020.
prof.dr.ir. G (Geert) Smant
Chairholder
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