In vitro research into food and human health

About this expertise
In short- In vitro models for food-health interaction research
- Nutrient characterisation and isolation
- Simulation of digestion, metabolism and immune responses
- Support for Novel Foods and health claims
We research the impact of food on human health using advanced in vitro models, nutrient analysis, and biological simulation. Our work supports industry innovation and regulatory approval.
Wageningen University & Research (WUR) offers a comprehensive platform for studying how food and nutrients affect human health. This research ranges from molecular analysis in the lab to simulation of digestive and metabolic processes. This way, we help businesses innovate responsibly and comply with legislation such as Novel Foods and health claims.
We use in vitro models to explore intestinal barrier function, nutrient digestion, microbiota fermentation, and interactions between food and the immune system. These studies are crucial for identifying health effects and often serve as a first step towards animal or human studies. They can also provide insights into underlying mechanisms observed in human studies.
In addition, we support companies with regulatory advice and documentation, guiding product development from early screening to compliant labelling and responsible consumer communication.
Wageningen also offers advanced tools for isolating and analysing nutrients, including protein purification for allergy research. Our technologies include chromatography, spectroscopy, volatile compound analysis (e.g. PTR-MS, GC-TOF), and various filtration methods.
Using simulation platforms like INFOGEST, SHIME, organoids and gut-on-a-chip models, we map digestion processes and health effects. We examine, among other things, nutrient bioavailability, metabolic responses, immune modulation, and microbiota dynamics.
Facilities (3)
Get in touch with our expert
Interested in the possibilities? Contact us for an informal conversation.
dr.ir. AP (Paul) Vos
senior researcher Nutrition Quality & Health


